Leflunomide is a medication commonly prescribed for rheumatoid arthritis and other autoimmune diseases. While it helps reduce joint inflammation and damage, it can also cause some side effects you should be aware of. Knowing these can help you stay safe and manage any problems early.
Many people taking leflunomide experience mild side effects like diarrhea, nausea, or headache. These symptoms may appear soon after starting the medication and often improve with time. Some might also notice hair thinning or a rash, which usually aren't serious but should still be mentioned to your doctor.
Besides these mild issues, leflunomide can sometimes affect liver function. That’s why doctors typically recommend regular blood tests to check liver enzymes during treatment. Signs you should never ignore include yellowing of the skin or eyes, dark urine, or persistent abdominal pain—these could hint at liver problems requiring urgent attention.
In rare cases, leflunomide may lower your white blood cell count, making infections more likely. You might notice fever, sore throat, or other signs of illness more often. If you do, it’s important to contact your healthcare provider promptly to avoid complications.
Because leflunomide can harm an unborn baby, it’s crucial to avoid pregnancy during treatment and for some time after stopping the drug. Both men and women should discuss family planning and contraception options with their doctor before starting this medication.
Before you begin leflunomide, tell your doctor about any liver issues, infections, or other health conditions. Also, notify them about all other medications you’re taking since leflunomide can interact with certain drugs.
Dealing with side effects might sound overwhelming, but staying informed and communicating openly with your healthcare team makes a big difference. Keeping close tabs on your health while on leflunomide ensures you get the benefits with less risk.
Published on May 17
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